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. Author manuscript; available in PMC: 2016 Jul 15.
Published in final edited form as: J Immunol. 2015 Jun 5;195(2):717–725. doi: 10.4049/jimmunol.1401250

Fig 8. HY-Specific iTregs spare the GVL effect.

Fig 8

B6D2F1 male recipient mice were lethally irradiated and injected with B6 BM with or without HY-specific iTregs, three days later CD25 depleted Teffs plus 5000 p815-luc mastocytoma cells were injected. Mice were monitored for body weight loss (A), survival (B), and tumor morality (C) using the IVIS 200 imager throughout the course of study. The data depicted in A and B is pooled from 2 replicate experiments, but the imaging shown (D) is from one of these 2 replicate experiments. Asterisk indicates statistical significance: *p<0.05, **p<0.01, ***p<0.001