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. Author manuscript; available in PMC: 2016 Jul 15.
Published in final edited form as: J Immunol. 2015 Jun 1;195(2):507–518. doi: 10.4049/jimmunol.1500027

Figure 7.

Figure 7

IL-13Rα1 exercises differential control of DC and basophil mediated T cell programing in vivo. MHC-II −/− IL-13Rα1+/+ Balb/c neonatal mice recipient of DCs or basophils from 1-day-old IL-13Rα1+/+ or IL-13Rα1−/− mice alongside neonatal DO11.10 T cells and the hosts were given Ig-OVA. On day 14, the SP cells from the MHC-II −/− IL-13Rα1+/+ hosts were harvested, supplemented with MHC-II-sufficient DCs from MHC-II+/+ IL-13Rα1+/+ mice (to serve as APCs) and the culture was stimulated with OVA peptide. Ex-vivo (dot plots) and recall (bar graphs) cytokines responses by CD4 T cells were then analyzed by intracellular staining and ELISA, respectively. (A and B) shows cytokine production by T cells from hosts recipient of (A) DCs or (B) basophils. Each bar represents the mean ± SD of triplicate wells. Data is representative of 2 experiments.