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. 2015 May;52(5):603–610. doi: 10.1165/rcmb.2014-0278OC

Figure 6.

Figure 6.

Macrophages from Treg-sufficient Foxp3gfp mice and Treg-deficient Foxp3DTR show similar levels of cytokine expression in vitro. Macrophages isolated from the lungs of Treg-sufficient Foxp3gfp mice and Treg-deficient Foxp3DTR mice 5 days after the onset of ischemia showed similar basal secretion of LIX and IL-6. Stimulation with a reactive oxidant (H2O2) showed a significant increase in cytokine secretion (n = 3–4 experiments/group; P = 0.01), but no difference between strains.