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. 2015 Apr 10;10(7):1291–1299. doi: 10.2215/CJN.00860115

Table 3.

Medications associated with thrombotic microangiopathy

Antineoplastic agents
 Antiangiogenesis drugs
 Mitomycin-C
 Gemcitabine
 Cisplatin/carboplatin
 Estramustine/lomustine
 Cytarabine
 Tamoxifen
 Bleomycin
 Daunorubicin
 Hydroxyurea
Antiplatelet agents
 Ticlopidine, clopidogrel, prasugrel
 Dipyradamole
 Defribrotide
IFNs
 IFN-α and -β
Immunosuppressive agents
 Calcineurin inhibitors
 Anti-CD33 (OKT3)
Antimicrobial agents
 Valacyclovir
 Penicillins
 Rifampin
 Metronidazole
 Tetracycline
 Sulfasoxazole
 Albendazole
Nonsteroidal anti–inflammatory drugs
 Diclofenac
 Piroxicam
 Ketorolac
Hormones
 Conjugated estrogens alone or combined with progestins
 Contraceptives, combination
Others
 Quinine
 Intravenous oxymorphone (Opana) ER
 Simvastatin
 Iodine
 Cocaine

ER, extended release.