Table 2.
Strains | MOI 1,000 | MOI 100 | MOI 10 |
---|---|---|---|
ATCC 33277 (K−) | 0% | 29% (±3) | 81% (±5) |
HG91 (K−) | 0% | 11% (±1) | 69% (±3) |
W83 (K1) | 23% (±3) | 70% (±5) | 91% (±3) |
ATCC49417 (K4) | 0% | 30% (±5) | 72% (±6) |
HG1691 (K6) | 17% (±2) | 48% (±4) | |
Heat-inactivated FimA mutant | 7% (±6) | 38% (±10) | 85% (±6) |
Viable FimA mutant | 0% | 23% (±2) | 75% (±5) |
K−, K1, K4, and K6 strains all significantly inhibited epithelial cell migration (p=0.001). ATCC 33277 and HG91 inhibited epithelial cell migration significantly more than K1 and K6 (p<0.002). K4 inhibited epithelial cell migration significantly more than K1 and K6 (p<0.001), K4 inhibited epithelial cell migration significantly less than HG91 but not ATCC 33277.