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. 2015 Jul 2;7:10.3402/jom.v7.27543. doi: 10.3402/jom.v7.27543

Table 2.

Relative closure (mean±SEM) of scratch in oral epithelial cells challenged with heat-inactivated P. gingivalis strains with several capsular serotypes and a fimbriae-lacking mutant

Strains MOI 1,000 MOI 100 MOI 10
ATCC 33277 (K−) 0% 29% (±3) 81% (±5)
HG91 (K−) 0% 11% (±1) 69% (±3)
W83 (K1) 23% (±3) 70% (±5) 91% (±3)
ATCC49417 (K4) 0% 30% (±5) 72% (±6)
HG1691 (K6) 17% (±2) 48% (±4)
Heat-inactivated FimA mutant 7% (±6) 38% (±10) 85% (±6)
Viable FimA mutant 0% 23% (±2) 75% (±5)

K−, K1, K4, and K6 strains all significantly inhibited epithelial cell migration (p=0.001). ATCC 33277 and HG91 inhibited epithelial cell migration significantly more than K1 and K6 (p<0.002). K4 inhibited epithelial cell migration significantly more than K1 and K6 (p<0.001), K4 inhibited epithelial cell migration significantly less than HG91 but not ATCC 33277.