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Ipilimumab serum concentration profile versus time during Cycle 3. Open circles, ipilimumab 3 mg/kg plus PTX/CBDCA group (n = 6); closed circles, ipilimumab 10 mg/kg plus PTX/CBDCA group (n = 6). Data are mean plus standard deviation. On Day 1 of Cycle 3, blood serum samples were drawn at the following time points: Pre-infusion, 1.5 h (just prior to the end of ipilimumab dosing), 4 h and 24 h
