Table 1.

Endophytic actinobacteria isolated from medicinal plants

Species of actinomycetes	Host plant	Tissue	Bioactive compounds	Reference
Streptomyces longisporoflavus, Streptomyces sp.	Rauwolfia densiflora	Stem, leaf, inflorescence	ND	Akshatha et al. (2014)
Amycolatopsis sp., Micromonospora sp., Streptomyces sp.	Siparuna crassifolia, Calycophyllum acreanum, Capirona decorticans, Ocotea longifolia, Aspidosperma sp, Palicourea longifolia, Monstera spruceana, Croton lechleri, Cantua buxifolia, Banisteriopsis caapi, Iryanthera laevis, Eucharis cyaneosperma	Stem	ND	Bascom-Slack et al. (2009)
Kineococcus endophytica	Limonium sinensis	ND	ND	Bian et al. (2012b)
Streptomyces phytohabitans	Curcuma phaeocaulis	Root	ND	Bian et al. (2012a)
Kitasatospora sp.	Taxus baccata	Wood/inner cortical tissues	Paclitaxel	Caruso et al. (2000)
Streptomyces sp. NRRL 30562	Kennedia nigriscans	Stem	Munumbicins A, B, C and D	Castillo et al. (2002)
Streptomyces sp. NRRL 30566	Grevillea pteridifolia	Stem	Kakadumycins	Castillo et al. (2003)
Streptomyces sp. NRRL 30562	Kennedia nigriscans	ND	Munumbicins E-4 and E-5	Castillo et al. (2006)
Pseudonocardia endophytica	Lobelia clavatum	Inner tissue	ND	Chen et al. (2009)
Micromonospora sp., Nonomuraea sp., Planotetraspor sp., Pseudonocardia sp.	Elaeagnus angustifolia	Root nodules	ND	Chen et al. (2011)
Microbispora sp.	Spermacoce verticillata	Leaf	ND	Conti et al. (2012)
Streptomyces sp.	Centella asiatica	Root, stem, leaf	Indole acetic acid (IAA)	Dochhil et al. (2013)
Allonocardiopsis opalescens	Lonicera maackii	Fruit	ND	Du et al. (2013b)
Streptomyces sp. Hedaya48	Aplysina fistularis	Inner healthy tissue	Vanillin, 5,7-dimethoxy-4-p-methoxylphenylcoumarin, Saadamycin	El-Gendy and EL-Bondkly (2010)
Streptomyces sp.	Artemisia herba-alba, Echinops spinosus, Mentha longifolia, Ballota undulate	Green aerial parts	ND	El-Shatoury et al. (2006)
Kibdelosporangium sp., Kitasatosporia sp., Nocardia sp., Nocardioides sp., Promicromonospora sp. Pseudonocardia sp., Streptomyces sp.	Achillea fragrantissima	ND	Siderophores, Chitinase	El-Shatoury et al. (2009)
Streptomyces sp. MSU-2110	Monstera sp.	Stem	Coronamycin	Ezra et al. (2004)
Actinopolyspora sp., Micromonospora sp., Saccharopolyspora sp., Streptomyces sp.	Aloe vera, Mentha, Ocimum sanctum	Root, stem, leaf	ND	Gangwar et al. (2011)
Actinopolyspora sp., Micromonospora sp., Saccharopolyspora sp., Streptomyces sp.	Aloe vera, Mentha arvensis, Ocimum sanctum	Root, stem, leaf	Hydroxamate-type of siderophore, Catechol-type of siderophore, Indole acetic acid (IAA)	Gangwar et al. (2014)
Streptomyces sp. TP-A0569,	Allium fistulosum	Leaf	Fistupyrone 7′-Demethylnovobiocin, 5″-demethylnovobiocin, Novobiocin, 6-Prenylindole, Anicemycin Pteridic acids A and B	Igarashi (2004)
Streptomyces hygroscopicus TP-A0451,	Pteridium aquilinum	Stem	Clethramycin
Streptomyces hygroscopicus TP-A0326,	ND	ND	Cedarmycins A and B
Streptomyces sp. TP-A0456	Cryptomeria japonica	Twig
Streptomyces hygroscopicus TP-A0451	ND	ND	Pterocidin	Igarashi et al. (2006)
Micromonospora lupini	ND	ND	Lupinacidins	Igarashi et al. (2007)
Streptomyces cavourensis AB184264.1	Catharanthes roseus	Leaf	ND	Kafur and Khan (2011)
Streptomyces laceyi MS53	Ricinus communis	Stem	6-Alkylsalicylic acids (salaceyins A and B)	Kim et al. (2006)
Actinomycetes sp.	Emblica officinalis	Twig, leaf	ND	Kumar et al. (2011)
Streptomyces sp.	Cistanches deserticola	Root	Tyrosol (possible ligand for GPR12) Phenylethylamine derivatives, Cyclic dipeptides, Nucleosides and their aglycones, N-acetyltryptamine and Pyrrole-2-carboxylic acid	Lin et al. (2008)
Streptomyces sp. CS	Maytenus hookeri	ND	24-demethyl-bafilomycin C1 (Naphthomycin A)	Lu and Shen (2003)
Streptomyces sp. CS	Maytenus hookeri	Tissue cultures	Naphthomycin K, A and E	Lu and Shen (2007)
Micromonospora sp., Nocardiopsis sp., Streptomyces sp.	Achillea millefolium, Aloe arborescens, Anthoxantum odoratum, Arctium lappa, Convallaria majalis, Fragaria vesca, Geranium pretense, Hippophae rhamnoides, Lysimachia nummularia, Matricaria matricarioides, Melilotus officinalis, Mentha arvensis, Plantago major, Rosa cinnamomea, Rubus idaeus, Tanacetum vulgare, Taraxacum officinale, Trifolium pretense Urtica dioica, Viola odorata	Leaf	ND	Machavariani et al. (2014)
Actinomadura sp. Kibdelosporangium sp., Kitasatosporia sp., Nocardioides sp., Pseudonocardia sp., Streptomyces sp., Undefinied actinomycetes	Phyllanthus niruri, Withania somnifera, Catharanthus roseus, Hemidesmus indicus	Root	Volatile organic compounds (VOCs), Diffusible metabolites Chitinase, Cellulases, CMC-ase,	Mini Priya (2012)
Actinomadura sp., Kibdelosporangium sp., Kitasatosporia sp., Nocardia sp., Nocardioides sp., Pseudonocardia sp., Streptomyces sp., Undefinied actinomycetes	Achillea fragrantissima, Catharanthus roseus, Artemisia herba-alba, A. judaica, Jasonia montan, Launae sp., Echinops spinosissimus, Pulicaria sp., Centauria sp., Nerium oleander	ND	Volatile organic compounds (VOCs), Diffusible metabolites	Moussa et al. (2011)
Actinomycete sp., Brevibacterium sp., Leifsonia sp., Microbacterium sp., Streptomyces sp.	Mirabilis jalapa, Clerodendrum colebrookianu, Eupatorium odoratum, Alstonia scholaris Musa superba	Leaf, stem, root, flower	ND	Passari et al. (2015)
Streptomyces olivochromogenes	Tinospora crispa Phaleria macrocarpa, Curcuma aeruginosa, Andrographis paniculata, Caesalpinia sappan, Curcuma xanthoriza, Gynura procumbens, Physalis peruviana, Hibiscus sabdariffa	Root, leaf, stem	Inhibitor of alpha-glucosidase	Pujiyanto et al. (2012)
Streptomyces setonii, Streptomyces sampsonii, Streptomyces sp. Q21, Streptomyces sp. MaB- QuH- 8	Maytenu saquifolia, Putterlickia retrospinosa, Putterlickia verrucosa	ND	Celastramycins A and B	Pullen et al. (2002)
Glycomyces endophyticus	Carex baccans	Root	ND	Qin et al. (2008b)
Glycomyces mayteni Glycomyces scopariae	Scoparia dulcis, Maytenus austroyunnanensis	Root	ND	Qin et al. (2009)
Pseudonocardia sichuanensis	Jatropha curcas	Root	ND	Qin et al. (2011)
Nocardioides panzhihuaensis	Jatropha curcas	Stem	ND	Qin et al. (2012a)
Actinomadura sp., Amycolatopsis sp, Cellulosimicrobium sp., Glycomyces sp., Gordonia sp., Janibacter sp., Jiangella sp., Microbacterium sp., Micromonospora sp., Mycobacterium sp., Nocardia sp., Nocardiopsis sp., Nonomuraea sp., Plantactinospora sp, Polymorphospora sp., Promicromonospora sp., Pseudonocardia sp., Saccharopolyspora sp, Streptomyces sp, Streptosporangium sp., Tsukamurella sp.	Maytenus austroyunnanensis	Root, stem, leaf	ND	Qin et al. (2012b)
Streptomyces sp.	Azadiracta indica, Ocimum sanctum, Phyllanthus amarus	Root, leaf	ND	Shenpagam et al. (2012)
Streptomyces antibioticus	Curcuma domestica, Phaleria macrocarpa, Isotoma longiflora, Symplocos cochinensis	Root, stem, leaf	ND	Sunaryanto and Mahsunah (2013)
Streptomyces aureofaciens CMUAc130	Zingiber officinale, Alpinia galanga	Root	ND	Taechowisan and Lumyong, (2003)
Microbispora sp, Micromonospora sp., Nocardia sp., Streptomyces sp., Unidentified isolates	Zingiber officinale, Alpinia galanga	Root, stem, leaf	ND	Taechowisan et al. (2003)
Streptomyces aureofaciens CMUAc130	Zingiber officinale	Root	5,7- dimethox y-4-p-methoxylphenylcoumarin, 5,7-dimethoxy-4-phenylcoumarin	Taechowisan et al. (2005, 2007)
Microbispora sp., Micromonospora sp. Nocardia sp., Streptomyces sp. Tc022, Unidentified isolates	Alpinia galanga	Root	Actinomycin D	Taechowisan et al. (2006)
Microbispora sp., Nocardia sp., Sacchromonospora sp., Streptomyces sp., Streptosporangium sp., Streptoverticillium sp.	Azadirachta indica	Root, stem, leaf,	ND	Verma et al. (2009)
Jishengella endophytica 161111	Xylocarpus granatum	Root	Alkaloids	Wang et al. (2014)
Saccharopolyspora dendranthemae	Dendranthema indicum	Stem	ND	Zhang et al. (2013)
Streptomyces sp. neau-D50	Soybean	Root	3-acetonylidene-7-prenylindolin-2-one (isoprenoids, 7-isoprenylindole-3-carboxylic acid, 3-cyanomethyl-6-prenylindole, 6-isoprenylindole-3-carboxylic acid and 7,40 -dihydroxy-5-methoxy-8-(g,g-dimethylallyl)-flavanone)	Zhang et al. (2014)
Micromonospora sp., Nonomuraea sp., Oerskovia sp., Promicromonospora sp., Rhodococcus sp., Streptomyces sp.	Potentilla discolor, Ainsliaea henryi, Impatiens chinensis, Rhizoma Arisaematis, Dioscorea opposita, Stellera chamaejasme, Salvia miltiorrhiza, Drosera peltata, var.multisepala, Artemisia annua, Achyranthes aspera, Cynanchum auriculatum, Gnaphalium hypoleucum, Mosla dianthera, Cassytha filiformis, Vaccinium bracteatum	Root, stem, leaf	ND	Zhao et al. (2011)
Streptomyces sp. YIM66017	Alpinia oxyphylla	ND	2,6-dimethoxy terephthalic acid, yangjinhualine A, α-hydroxyacetovanillone and cyclo(Gly-Trp)	Zhou et al. (2014)

ND no data