Table 1.

Demographics and clinical characteristics in T2DM group and control group

		T2DM group	Control group	p
Gender	Men (n)	95	128	0.64
	Women (n)	93	138
Age (year)		60.97 ± 9.05	60.50 ± 10.85	0.59
Educational status (year)		9.32 ± 3.80	10.18 ± 3.95	0.02
Fasting blood glucose(mmol/L)		8.65 ± 4.01	4.99 ± 0.65	<0.001
HbA1c (%)		8.45 ± 2.19	5.70 ± 0.29	<0.001
Hypertension (n)		134(71.28 %)	124(46.62 %)	<0.001
Systolic pressure(mmHg)		136.76 ± 11.15	130.17 ± 10.58	<0.001
Diastolic pressure(mmHg)		87.02 ± 6.04	84.13 ± 4.90	<0.001
Hyperlipidemia (n)		53(28.19 %)	52(19.55 %)	0.04
Cholesterol(mmol/L)		4.76 ± 1.13	4.82 ± 1.07	0.66
Triglycerides(mmol/L)		2.05 ± 1.74	1.61 ± 1.10	0.02
HDL(mmol/L)		1.18 ± 0.35	1.35 ± 0.49	0.001
LDL(mmol/L)		3.00 ± 0.88	3.07 ± 0.98	0.52
Cardiovascular disease (n)		60(31.91 %)	56(21.05 %)	0.01
Smoking habits (n)		72(38.30 %)	72(27.07 %)	0.01
BMI		24.40 ± 2.74	23.19 ± 3.01	<0.001
Cerebral structural changes (n)		156(82.98 %)	209(78.57 %)	0.28
MMSE		25.09 ± 4.29	26.06 ± 3.81	0.01
MoCA		18.81 ± 5.63	20.76 ± 5.02	<0.001
Memory quotient		78.24 ± 21.92	88.50 ± 18.76	0.08
Left hippocampus	NAA	0.072 ± 0.088	0.064 ± 0.079	0.15
	Cr	0.066 ± 0.076	0.049 ± 0.053	0.01
	Cho	0.055 ± 0.091	0.053 ± 0.055	0.18
	mI	0.064 ± 0.071	0.044 ± 0.058	0.02
Left frontal lobe	NAA	0.348 ± 0.350	0.353 ± 0.365	0.51
	Cr	0.234 ± 0.239	0.237 ± 0.265	0.41
	Cho	0.206 ± 0.201	0.199 ± 0.268	0.41
	mI	0.136 ± 0.167	0.127 ± 0.266	0.33