. 2015 Apr 16;30(4):1027–1034. doi: 10.1007/s11011-015-9670-4

Table 4.

Multiple linear regression analyses of brain metabolites in the left hippocampus and left frontal lobe, and interference factors for metabolite changes in all participants

	Left hippocampus				Left frontal lobe
	NAA	Cr	mI	Cho	NAA	Cr	mI	Cho
Constant	0.182	0.046	0.154	0.170	0.276	−0.074	−0.594	4.801
Gender	0.027	0.077	0.034	0.199	−0.022	0.025	0.026	0.422
Age	−0.002	−0.001	−0.002	−0.002	0.005	0.004	0.011	−0.049
Hypertension	−0.022	−0.085	−0.062^b	−0.188	0.009	0.057	0.170	0.946
Hyperlipidemia	0.020	0.059	0.011	0.232^a	−0.060	−0.057	−0.184	−0.495
Cardiovascular disease	0.023	0.120^b	0.080^b	0.246^a	−0.110	−0.098	−0.286	−0.303
Smoking habits	0.011	0.081	0.029	0.045	−0.007	0.002	0.282	−0.159
Cerebral structural changes	−0.063^a	−0.007	0.027	−0.046	−0.061	0.035	0.017	0.865
BMI	−0.004	−0.002	−0.003	−0.010	0.000	0.004	0.010	−0.111
T2DM	0.042	0.153^b	0.057^b	0.166	−0.031	−0.039	−0.206	−0.436

a p < 0.05

b p < 0.01