Fig. 6.

Dose-dependent effects of VEGF on the Glut-1 and Bcl-2 during hypoglycemia in bEnd.3 cells. Confluent bEnd.3 cells were treated with 5.5 mM (control) glucose and 0.5 mM glucose for 24 h in the absence or presence of different concentrations of VEGF (0, 10, 50, and 100 ng/mL). (a) Representative Western blots of Glut-1 and Bcl-2 with β-actin as a protein loading control. Summary plots of Bcl-2 (b) and Glut-1 (c) with densitometric analyses of the corresponding protein blots. Data are expressed as mean ± SEM. N = 3. ^* P < 0.05, ^** P < 0.01