Table 1.
Composition of all formulations and targeted hardness of the tablets.
Formula name | Lisinopril (wt%) | Compritol (wt%) | Avicel pH-101 (wt%) | Lactose (wt%) | Dibasic CaPO4 (wt%) | Distilled water (mL) | Targeted hardness (kP) |
---|---|---|---|---|---|---|---|
LCAD | 10 | 30 | 30 | 0 | 30 | 370 | 6.5–9 |
LCA60 | 10 | 30 | 60 | 0 | 0 | 700 | 4 |
LCAL | 10 | 30 | 30 | 30 | 0 | 400 | 7–9 |
LC50A40 | 10 | 50 | 40 | 0 | 0 | 560 | 4–5 |