Fig. 1.

Conservation of glutathione S-transferase (GST) mu class elements and protein signature motifs in the N-terminal region of two GSTs derived from Dermanyssus gallinae. The N-terminal regions of two D. gallinae GST proteins (Deg-GST1 and Deg-GST-3) were aligned using the ClustalX algorithm with their two closest BLASTp matches: Metaseiulus occidentalis (XP_003742682.1 and XP_003747409.1), Nematostella vectensis (XP_001634653.1) and Haemaphysalis longicornis (AAQ74441.1). The signature motifs of mu class GSTs are annotated as follows: the conserved tyrosine active site residue (black shading), the four mu class elements (PR01267, bold and underlined) and the mu-loop structure (grey shading). The amino acid insertions conserved in Deg-GST-1 and XP_003747409.1 are in bold