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. Author manuscript; available in PMC: 2015 Jul 5.
Published in final edited form as: Atherosclerosis. 2013 Dec 6;232(2):369–376. doi: 10.1016/j.atherosclerosis.2013.11.042

Table 6. CHD events in MESA participants by family history of coronary heart disease and aggregate incidence and progression of CAC.

No Family Hx Late Family Hx Premature Family Hx
Incidence/Progression? Negative Positive Negative Positive Negative Positive
Person-Years 9099 4797 5206 3922 3192 2241
CHD Events 22 53 17 63 10 26
Events per 1000 person-years 2.4 11 3.3 16.1 3.3 10.7
95% CI 1.6-3.7 8.3 - 14.5 2.0-5.3 12.5 - 20.6 1.7-5.8 7.3-15.6

Positive incidence/progression represents any CAC incidence or absolute CAC change ≥ 25 volume units with accompanying adjusted CAC percentage change ≥ 25% per 3 years (median time between scans). CHD: coronary heart disease