Table 3.
Diaphragm muscle properties across the lifespan in mice
| Two-Way ANOVA P Value |
|||||
|---|---|---|---|---|---|
| Male | Female | Age effect | Sex effect | Interaction | |
| Pt, N/cm2 | <0.001 | 0.166 | 0.358 | ||
| Young | 6.2 ± 0.3 | 6.4 ± 0.3 | |||
| Old* | 4.3 ± 0.5 | 5.1 ± 0.3 | |||
| Pt/Po | 0.474 | 0.354 | 0.881 | ||
| Young | 0.31 ± 0.01 | 0.32 ± 0.01 | |||
| Old | 0.33 ± 0.03 | 0.34 ± 0.02 | |||
Values are means±SE (n = 8/group). Maximal twitch force (Pt) and isometric tetanic force (Po) are normalized to physiological cross-sectional area.
Significantly different from young group.