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. 2015 Apr 7;47(7):243–252. doi: 10.1152/physiolgenomics.00010.2015

Fig. 2.

Fig. 2.

Fecal electrical current production is transferrable via material adherent to ileal mucosa and correlates with lymphocyte recruitment. Current production was measured in MECs inoculated with fecal samples (A, n = 4) or ileal mucosal scrapes (B, n = 1) collected from C57BL/6J or C57BL/6NHsd mice. Data from Jackson (Jax) and Harlan (HSD) mice are shown in green and orange, respectively. C: current production by fecal samples collected from 12 C57BL/6J recipients prior to gavage. D: current production in MECs inoculated with feces collected from recipients 48 h postgavage with ileal scrape material collected from C57BL/6NHsd (orange) or C57BL/6J (green) mice or following no gavage (blue). Current (μA) is shown as mean ± SE. E: immunohistochemical staining of ileal tissue for CD3 was performed in recipient mice 6 wk postgavage with ileal scrape material. Mean (± SE) number of CD3+ (F) and B220+ (G) cells per villus. Bars denote P ≤ 0.05 as determined via Mann-Whitney nonparametric analysis. H: immunohistochemical staining for CCL21 in the ileum of recipient mice 6 wk postgavage.