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. 2015 Jun 15;7(2):981–1004. doi: 10.3390/cancers7020820

Table 2.

Chest wall and related toxicity characteristics.

Toxicity Incidence Timing Dosimetric Correlates Study
Volume Dose Fraction
Chest Wall Pain 30% risk (Range: 10% to 44%) 12.6 months post-SBRT (Range: 4.3–35.9 months) 30 cc of chest wall 30 Gy 3 (Range:3–5) Dunlap et al., 2010 [89]
Mutter et al., 2012 [84]
Creach et al., 2012 [87]
Rib Fracture 5% risk 19.2 months post-SBRT 2 cc of rib 27 Gy 3 Pettersson et al., 2009 [88]
50% risk 2 cc of rib 50 Gy 3 Creach et al., 2012 [87]
Skin Toxicity 1.2%–14% 3–6 weeks post-SBRT <10 cc volume, volume maximum of 30 Gy 6 Gy/fraction 5 RTOG 0813 [91]
Hoppe et al., 2008 [92]
maximum point dose of 32 Gy, maximum posterior skin dose ≥50% of actual prescribed dose 6.4 Gy/fraction 5