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. 2015 Jul 7;16(1):501. doi: 10.1186/s12864-015-1642-x

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© Khan et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Modulation of metastamiRs target proteins in MSDACs ex vivo and in metastatic tumors in vivo. Immunoblots showing the expressional modulation of key metastatsis and tumor progression related protein targets of the identified metastamiRs in (a) parental SH-SY5Y cells vs MSDACs under ex vivo conditions and; (b and c) non-metastatic xenograft vs manifold of metastatic tumors from aggressive disease animals in vivo