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. 2015 Jul 7;7(1):61. doi: 10.1186/s13148-015-0098-9

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© Lleo et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Correlation analysis was performed to evaluate the relationship between CXCR3 gene expression levels, methylation status of CXCR3 promoter, and disease duration. a CXCR3 expression in CD4+ T cells inversely correlates with methylation status of CXCR3 promoter. b CXCR3 expression in CD4+ T cells correlates with disease duration. Real-time threshold cycle values for CXCR3 cDNA were normalized with GADPH and compared to a calibrator. Calibrated CXCR3 expression levels were correlated to disease duration (months). 95 % confidence limits of the best-fit line are shown (solid line)