Table 2.
PBC patients | Healthy controls | |
---|---|---|
(n = 30) | (n = 30) | |
Mean age (years, range) | 64 (44–87) | 60 (42–79) |
Females (n, %) | 30 (100 %) | 30 (100 %) |
AMA positivity (n, %) | 28 (93 %) | n.a. |
Liver cirrhosis (n, %) | 4 (13 %) | n.a. |
Total bilirubin (mg/dl) (n.v. <1.0) | 0.64 ± 0.39 | 0.73 ± 0.18 |
Alkaline phosphatase (IU/l) (n.v. <279) | 152.3 ± 207.3 | 168 ± 24 |
Alanine aminotransferase (U/l) (n.v. <50) | 33 ± 26 | 32 ± 9 |
Albumin (g/dl) (n.v. >3.5) | 4.33 ± 0.86 | 4.68 ± 0.03 |
Length of follow-up (months, range) | 34 (14–56) | n.a. |
Therapy with UDCA (n, %) | 28 (93 %) | n.a. |
Liver biopsy (n, %) | 21 (72 %) | n.a. |
Mean values ± standard deviation unless otherwise stated
n.a. not applicable, n.v. normal value