FIGURE 4.
Influence of NGF-Ab on O3-induced changes in SP levels in bronchoalveolar lavage fluid and lung tissue. Animals were instilled with IgG or NGF-Ab (both at 1:2000 dilution, 4 ml/kg) prior to O3 exposure. SP levels were measured in bronchoalveolar lavage fluid and lung tissue by an ELISA 24 h after O3 exposure (2 ppm, 3 h). (A) SP levels in lung lavage; (B) SP levels in the lung tissue. Values are means ± SE of 5 mice/group. Asterisk indicates significant difference in SP levels between IgG- and NGF-Ab-treated animals in both lung lavage and lung tissue (p ≤ .05).