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Multivariate analysis
| Adjust variables | Crude analysis | Adjusted analysis |
| Total (n = 351) | ||
| Age starting thiopurine older than 40 vs 40 or younger | OR (95%CI) | |
| Female | 3.6 (1.9-7.1) | 4.0 (1.9-8.3) |
| Male | 1.2 (0.6-2.6) | 1.3 (0.6-3.0) |
Predictors of thiopurine-related adverse events as determined by multivariate analysis. A significant age-by-gender interaction was observed in both crude and adjusted analyses, P-value = 0.03 and 0.04 respectively.
