Fig. 5.
The capability of circulating exosomes into kidney tissue. PKH67-labeled exosomes or unlabeled exosomes were injected into circulating blood of rats. The kidneys were isolated to determine the PKH67-labeled exosomes in the kidney tissue sections (A). HE-staining and fluorescence signal detection (green color) in kidney sections from unlabeled exosomes-injected animals. No fluorescence signal (green color) is demonstrated. (B) HE-staining and fluorescence signal detection (green color) in kidney sections from PKH67-labeled exosomes-injected animals. Fluorescence signal (green color) is identified.