Table 4.
Risk Factors for Central Line-Associated Blood Stream Infection in Neonatal Intensive Care Unit patients with Peripherally Inserted Central Catheters
| Univariate | Multivariable | |||||
|---|---|---|---|---|---|---|
| IRRa | 95% CI | P | IRR | 95% CI | P | |
| Gestational age category | ||||||
| <32 weeks | 1.00 | 1.00 | ||||
| ≥ 32 weeks | 0.40 | 0.14, 1.19 | 0.10 | 0.50 | 0.08, 3.18 | 0.46 |
| Birth weight category | ||||||
| <1500 grams | 1.00 | 1.00 | ||||
| ≥1500 grams | 0.45 | 0.16, 1.22 | 0.12 | 0.94 | 0.17, 5.18 | 0.94 |
| Chronological age | ||||||
| ≤ 7 days | 1.00 | 1.00 | ||||
| > 7 days | 1.44 | 0.59, 3.46 | 0.42 | 1.34 | 0.56, 3.25 | 0.51 |
| Days since PICC Insertion | ||||||
| < 19 days | 1.15b | 1.05, 1.26 | <0.01 | 1.14 | 1.04, 1.25 | <0.01 |
| 19-35 days | 0.80b | 0.67, 0.96 | 0.02 | 0.80 | 0.66, 0.96 | 0.02 |
| After 35 days | 1.32b | 1.12, 1.55 | <0.01 | 1.33 | 1.12, 1.57 | <0.01 |
IRR - Incidence Rate Ratio; CI – Confidence interval; PICC- peripherally inserted central catheters
a
Calculated using Poisson regression
b
IRR represents change in incidence rate per day within each time interval