Figure 4.
Design and operation of reagent delivery module (RDM). (a) Schematic of fluid path. The actual module has 8 reagent reservoirs but only 4 are shown for clarity. Reagent reservoirs are connected to a common path leading to a single output connection. Due to a small amount of carryover in the fluid path after reagent delivery, care must be taken in selection of reagent positions to mitigate effects of cross-contamination (or multiple RDMs can be used). Remaining panels show operating states: (b) User loads reagents through check-valves into reagent reservoirs during setup prior to synthesis. These reagents are stored in the reservoirs until needed. (c) Reagent #2 is delivered to the common delivery line with nitrogen pressure.