Table 3.

Significantly activated main clusters (p<0.05 voxel level for FDR, corrected) for adult, aged, and stroke subjects in each task. L left side, R right side, M medial/midline, SMA supplementary motor area

Region	Bimanual finger tapping task					Buttoning ADL task					Zipping ADL task
	Side	Talairach coordinates in MNI space			Z	Side	Talairach coordinates in MNI space			Z	Side	Talairach coordinates in MNI space			Z
		x	y	z			x	y	z			x	y	z
Adult subjects (18–50 year)
Sensorimotor	L	−24	−20	60	5.15	L	−36	−32	55	5.95	L	−40	−32	60	5.50
Sensorimotor	R	36	−24	60	4.86	R	40	−24	50	5.57	R	32	−12	60	4.45
Insula	L	−56	0	25	4.94						R	44	0	5	3.90
Cerebellum	R	16	−56	−20	4.65	M	0	−68	−10	4.71	R	8	−64	−15	5.01
Cerebellum	M/B	−4	−64	−20	5.14	M	4	−56	−10	5.21	M/R	8	−64	−15	5.01
Cerebellum	L	−20	−64	−20	4.95	L	−20	−60	−20	5.10	LR	−20	−68	−20	4.04
Aged subjects (>50 year)
Sensorimotor	R	32	−20	60	5.49	R	40	−24	55	5.86	R	32	−20	65	4.91
Sensorimotor											R	36	−44	65	3.91
Sensorimotor	L	−40	−36	60	5.13	L	−40	−44	60	4.72	L	−36	−32	60	4.84
SMA	M	0	−4	65	5.95	M	4	−4	55	4.64	M	−4	−12	70	3.51
Cerebellum	M	0	−68	−15	4.87	M/B	0	−60	−15	4.99	M/R	12	−56	−20	3.97
Cerebellum						R	24	−56	−50	3.85
PMAd	R	52	8	35	4.00
PMAv	R	56	8	10	3.84
Stroke subjects
SMA	M	0	−8	60	5.57	M	0	−20	75	5.31	M	−4	−16	55	4.32
Sensorimotor	R	40	−28	60	5.49	R	32	−20	60	5.34	R	36	−52	60	4.34
Sensorimotor	L	−36	−28	60	5.26	L	−36	−28	65	5.34	L	−32	−28	60	4.52
Cerebellum	M	−4	−64	−15	4.82	M	0	−68	−15	5.27	M	0	−68	−15	4.20