Table 2.
HRs and 95% CIs for colorectal cancer according to alcohol consumption in the Korean Multi-center Cancer Cohort, 1993–2005
| Men | Women | |||||||
|---|---|---|---|---|---|---|---|---|
|
|
|
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| Number (%) | Person-year | Colorectal cancer case (n) | HR (95% CI)a | Number (%) | Person-year | Colorectal cancer case (n) | HR (95% CI)a | |
| Alcohol consumption history | ||||||||
| Never drinker | 1,845 (24.6) | 20,102.6 | 22 | ref. | 8,660 (78.5) | 103,189.0 | 90 | Ref. |
| Former drinker | 783 (10.5) | 7,880.6 | 10 | 0.92 (0.43–1.96) | 234 (2.1) | 2,452.1 | 3 | 1.29 (0.40–4.16) |
| Current drinker | 4,827 (64.5) | 51,650.7 | 79 | 1.70 (1.05–2.76) | 2,072 (18.8) | 23,413.3 | 15 | 0.85 (0.49–1.47) |
| Missing | 33 (0.4) | 345.8 | 1 | 2.08 (0.28–15.71) | 68 (0.6) | 737.1 | 0 | |
| Duration of alcohol consumption (yr) | ||||||||
| Never drinker | 1,845 (24.6) | 20,102.6 | 22 | ref. | 8,660 (78.5) | 103,189.0 | 90 | Ref. |
| < 15 | 704 (9.4) | 8,016.2 | 1 | 0.31 (0.04–2.27) | 975 (8.8) | 11,339.2 | 8 | 1.09 (0.53–2.26) |
| 15–29 | 2,111 (28.2) | 23,552.6 | 23 | 1.32 (0.72–2.44) | 793 (7.2) | 8,683.7 | 7 | 0.96 (0.44–2.08) |
| ≥ 30 | 2,377 (31.7) | 23,129.3 | 60 | 1.93 (1.17–3.18) | 284 (2.6) | 2,909.1 | 1 | 0.33 (0.05–2.34) |
| Missing | 451 (6.0) | 5,179.1 | 6 | 0.99 (0.40–2.46) | 322 (2.9) | 3,670.5 | 2 | 0.67 (0.16–2.74) |
| Alcohol consumption amount (g/d) | ||||||||
| Never drinker | 1,845 (24.6) | 20,102.6 | 22 | ref. | 8,660 (78.5) | 103,189.0 | 90 | Ref. |
| < 10 | 1,823 (24.3) | 19,271.4 | 24 | 1.28 (0.71–2.31) | 1,408 (12.8) | 14,953.8 | 9 | 0.82 (0.41–1.63) |
| 10–29 | 1,282 (17.1) | 13,115.5 | 20 | 1.77 (0.96–3.26) | 264 (2.4) | 2,792.1 | 2 | 0.95 (0.23–3.87) |
| ≥ 30 | 1,723 (23.0) | 17,270.9 | 38 | 2.24 (1.31–3.84) | 151 (1.4) | 1,666.3 | 1 | 0.76 (0.11–5.44) |
| Missing | 815 (10.9) | 10,219.4 | 8 | 0.77 (0.34–1.75) | 551 (5.0) | 7,190.3 | 6 | 0.97 (0.42–2.24) |
HR, Hazard ratio; CI, confidence interval; Ref., reference.
a
Adjusted for body mass index (kg/m2; < 18.5, 18.5–22, 23–24, ≥ 25), moderate physical activity (h/wk; never, 0.5–6, ≥ 7), and cigarette smoking history (never smoker, former smoker, current smoker).