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. 2015 Mar 30;200(2):505–521. doi: 10.1534/genetics.115.175711

Figure 4.

Figure 4

Transcription at all 32 telomeres in WT and sir2Δ strains. RNA-Seq was performed on WT and sir2Δ strains. Shown are read pileups from WT (black) and sir2Δ (green). Read pileups are normalized to the median genome-wide coverage and are the average of three biological replicates. Genes that showed a twofold or greater increase in expression in all three sir mutants (sir2Δ, sir3Δ, and sir4Δ) are colored as red arrows. Genes that showed no significant change in expression between WT and all three sir mutants are in black.