Figure 4.

Schematic representation of the reporter gene constructs used. (A and B) ph-p promoter (A) and CG3835 promoter (B) are driving the E. coli lacZ gene. Blue lines give the relative location of the sequence variants in the 5-kb intergenic region containing the PRE and the promoters of ph-p and CG3835. The solid lines and numbers correspond to the five highly differentiated candidate SNPs that mark the different haplotype groups. Dashed lines indicate the other two sequence variants that differ between the African and European strains from which the intergenic region incorporated in the constructs originated.