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. 2015 Apr 24;200(2):633–649. doi: 10.1534/genetics.115.175380

Table 1. Accuracy of parameter estimates using the composite-likelihood, iHS, and nSL methods.

Parameters Composite likelihood iHS nSL
Ra α Statistical power (%)b α^ mean ± SD x^ deviation mean (median)c Exact site detected (%)d Statistical power (%)b x^ deviation mean (median)c Exact site detected (%)d Statistical power (%)b x^ deviation mean (median)c Exact site detected (%)d
Using both polymorphic and monomorphic sites
2000 1000 57 (17) 1160 ± 660 3.68 (1.73) 9.23 [10.9] 24 5.67 (2.91) 4.92 [5.29] 41 4.72 (2.23) 11.1 [13.1]
2000 86 (36) 2070 ± 920 4.11 (2.43) 10.6 [12.7] 63 6.18 (4.05) 3.54 [3.22] 63 5.01 (2.95) 9.4 [11.4]
4000 97 (30) 3850 ± 1780 6.03 (3.92) 9.07 [10.7] 89 8.58 (6.09) 2.61 [2.23] 76 7.10 (4.45) 6.9 [7.0]
4000 1000 35 (16) 1290 ± 840 2.92 (0.95) 15.6 [20.4] 9.6 5.71 (1.80) 7.37 [9.00] 42 3.36 (1.21) 18.6 [24.5]
2000 75 (40) 2290 ± 1000 2.51 (1.39) 15.9 [19.2] 41 3.98 (2.30) 5.46 [6.58] 73 2.77 (1.62) 16.3 [17.1]
4000 94 (48) 4030 ± 1610 3.56 (2.20) 13.8 [16.7] 78 5.12 (3.45) 3.90 [4.29] 87 3.66 (2.35) 12.6 [12.4]
Using only polymorphic sites
4000 1000 4.0 860 ± 950 3.62 13.3
2000 36 1630 ± 1010 3.21 13.3
4000 82 3290 ± 1870 4.91 10.3
a

Scaled recombination rate (4Nr) across the 100-k-long simulated sequence.

b

Percentages of simulated samples that yield P < 0.001. In parentheses: using an adjusted recombination rate in neutral simulations to yield mean LD identical to that of data to be analyzed.

c

Mean (median) deviation in kilobases of the estimated location of selection from the true location (x = 50,000): |x^50,000|×103.

d

Percentages of simulated samples for which x^ = 50,000. Those of samples in which the frequency of the beneficial allele is exactly 10 are given in brackets.