Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 May 13;24(15):4417–4428. doi: 10.1093/hmg/ddv178

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Published by Oxford University Press 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

PMC Copyright notice

Figure 7. — Rpe65^P25L/P25L KI mice are protected from light damage. Eyeballs from WT (A–D) and KI/KI (E–H) mice were treated with high-intensity light (20 000 lux) for 30 min following pupil dilation. Retinal integrity was monitored by OCT before (A and E) and 2 weeks after light damage (B and F). Fine retinal structures after light exposure were examined by light microscopic analysis of sections of retinal tissues of WT mice (C) and KI/KI mice (G). Cell apoptosis after light treatment was surveyed via TUNEL staining of frozen sections of retinae of WT mice (D) and KI/KI mice (H). Thickness of the total retina (I) and the photoreceptor layer (J) before and after light damage was measured on 10 WT and 15 KI/KI mice. Error bars show ±SD; *P < 0.05.