Table I.
Previous studies on the prevalence of depressive disorders in patients with ALS.
| Study | n | Assessment tool | Clinical criteria | Prevalence of depression |
|---|---|---|---|---|
| Houpt et al., 1977 (17) | 40 | Structured clinical interview | no | 35% |
| Schiffer et al., 1984 (18) | 84 | Chart review | no | Less than 5% |
| Newrick et al., 1984 (19) | 45 | Unstructured clinical interview | no | 7% |
| Bocker et al., 1990 (20) | 16 | Self-report | no | 75% |
| Hogg et al., 1994 (21) | 52 | Rating scale | no | 44% |
| Tedman et al., 1997 (22) | 40 | Rating scale | no | 30% |
| Moore et al., 1998 (23) | 18 | Rating scale | no | 23% |
| Ganzini et al., 1998 (24) | 100 | Structured clinical interview | yes | MDD = 11% |
| Rabkin et al., 2000 (25) | 56 | Structured clinical interview (SCID) | yes | MDD = 2% |
| Miller et al., 2000 (26) | 1707 | Self-report | no | 31.3% |
| Bungener et al., 2005 (27) | 27 | Semi-structured clinical interview | yes | MDD = 0% |
| Rabkin et al., 2005 (28) | 80 | Clinical interview (Patient Health Questionnaire) | yes | MDD = 9% |
| Wicks et al., 2007 (29) | 190 | Two self-report measures | no | 56%; 13% |
| Hammer et al., 2008 (30) | 39 | Structured clinical interview (SCID) | yes | MD = 10% |