Table 1. Effects of exposure to leptin or estradiol on rat dams’ pregnancy weight gain.

Rats were administered DMBA at 50 days of age and mated 2 weeks later. Pregnant dams were exposed to leptin, estradiol or vehicle control between days 8 of and 19 of gestation. Body weight values (in grams) collected at base-line and on the last week of gestation are expressed as the mean ± SEM. There were no significant differences in pregnancy weight gain among the groups.

Treatment	Baseline (g) (mean ± SEM)	Third week of gestation (g) (mean ± SEM)	Net weight gain (g) (mean ± SEM)
Control	223.98 ± 2.15	267.92 ± 3.04	43.20 ± 4.16
Leptin	224.39 ± 2.52	266.44 ± 2.82	42.59 ± 1.53
Estradiol	224.00 ± 1.94	264.76 ± 2.13	40.90 ± 1.83