Table 1.

Clinocopathologic characteristics of ovarian endometrioid and clear cell carcinomas with and without MMR protein loss of expression (LOE).

	MMR LOE (n = 7)	Normal MMR (n = 83)	P value
Age at diagnosis	47 y (39–53 y)	58 y (38–84 y)	0.014
Incidence under age 53
≤53 y	100% (7)	34% (28)	<0.001
>54 y	0% (0)	66% (55)
Synchronous or metachronous malignancy
Other primary malignancy	86% (6)	13% (11)	<0.001
No other primary malignancy	14% (1)	87% (72)
Histology
Clear cell	14% (1)	38% (32)	n.s.
Endometrioid	86% (6)	57% (47)
Mixed	0% (0)	5% (4)
Tumor grade
1	29% (2)	20% (17)	n.s.
2/3	71% (5)	80% (66)
FIGO stage
I	71% (5)	72% (60)	n.s.
II–IV	29% (2)	28% (23)
Five year overall survival rate	50%	57%	n.s.