Table 6. Frequency of worst acute toxicity and late toxicity in 205 nasopharyngeal carcinoma patients treated with volume-modulated arc therapy.
| Grade | Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|---|
| Acute Toxicity * | Cases (%) | Cases (%) | Cases (%) | Cases (%) | Cases (%) |
| Dermatitis | — | 135 (66) | 60 (29) | 10 (5) | 0 (0) |
| Mucositis | — | 45 (22) | 103 (50) | 57 (28) | 0 (0) |
| Dry mouth | — | 55 (27) | 121 (59) | 21 (10) | 0 (0) |
| Vomiting | — | 57 (28) | 25 (12) | 21 (10) | 0 (0) |
| Leucopenia | — | 33 (16) | 16 (8) | 8 (4) | 0 (0) |
| Neutropenia | — | 22 (12) | 22 (12) | 6 (3) | 0 (0) |
| Anaemia | — | 49(24) | 12 (6) | 4 (2) | 0 (0) |
| Thrombocytopenia | — | 16 (8) | 4 (2) | 4 (2) | 0 (0) |
| Fever | — | 8 (4) | 4 (2) | 2 (1) | 0 (0) |
| Weight loss | — | 71 (35) | 6 (3) | 0 (0) | 0 (0) |
| Liver function derangement | — | 27 (13) | 4 (2) | 0 (0) | 0 (0) |
| Late toxicity & | |||||
| Xerostomia | 53(26) | 133(65) | 14(7) | 4(2) | 0(0) |
| Ear | 111(54) | 58(28) | 30(15) | 6(3) | 0(0) |
| Cranial nerve | 202(98.5) | 1(0.5) | 1(0.5) | 1(0.5) | 0(0) |
| Spinal cord | 198(96) | 6(3) | 1(0.5) | 0(0) | 0(0) |
| Mandible | 197(96) | 6(3) | 2(1) | 0(0) | 0(0) |
| Skin | 170(83) | 31(15) | 4(2) | 0(0) | 0(0) |
| Subcutaneous tissue | 174(85) | 27(13) | 4(2) | 0(0) | 0(0) |
* graded according to the Common Terminology Criteria for Adverse Events v3.0 (CTCAE 3.0)
& graded according to Radiation Therapy Oncology Group (RTOG) Late Radiation Morbidity Scoring Criterion