FIG. 1.

Effects of SLCP formulations on: (a) Nitrite and (b) PGE₂ production in LPS-stimulated RAW 264.7 cells. Cells were co-treated with LPS (50 ng/mL) and samples (10, 25, and 50 μg/mL) for 24 h. SLCP-1 and SLCP-2 inhibited NO and PGE₂ levels in LPS-stimulated macrophages in a concentration-dependent manner. Data are expressed as mean values±SD. ^aP<.001 and ^bP<.01 indicate a significant difference as compared with the LPS-treated group. LPS, lipopolysaccharide; NO, nitric oxide; PGE_2, prostaglandin-E₂; SLCP, solid lipid curcumin particle.