Skip to main content
. 2015 Jul 6;10(7):e0132411. doi: 10.1371/journal.pone.0132411

Fig 5. Nifedipine and diazoxide suppressed PA-induced phosphorylation of JNK.

Fig 5

(A) After MIN6 cells were treated in 0.5 mM PA with/without different concentration of nifedipine for 48 h, the phosphorylation of JNK was detected by western blot. (B) The phosphorylation rate of JNK was calculated as optical density of phosphorylated-JNK (p-JNK) divide by total JNK (t-JNK). * p<0.05; *** p<0.001 denote significant difference versus the PA-treated alone group, n = 3. (C) After the cells were treated in 0.5 mM PA with/without different concentration of diazoxide, the phosphorylation of JNK was detected by western blot. (D) The phosphorylation rate of JNK was calculated. *** p<0.001 denote significant difference versus the PA-treated alone group, n = 3.