FIG. 10.

(A) The impact of high cervical lateral hemisection (C2Hx) on ipsilateral locomotor function was assessed during open field-locomotion using the Forelimb Locomotor Scale (FLS). Representative images depict locomotor function prior to and at 1 and 16 weeks post-injury. (B) FLS scores were determined in uninjured rats and at 1, 2, 4, 6, 8, 10, 12, 14, and 16 weeks post-C2Hx injury. All post-injury ipsilateral data points were significantly different than the contralateral (^%p<0.05) scores, and were significantly different than pre-injury values (*p<0.05). Progressive improvements in forelimb locomotor function occurred beginning in week 8, with each successive data point increasing significantly from the 6 week time point (^#p<0.05). Values are mean ± SE using one-way repeated measures analysis of variance (RM ANOVA). p<0.05.