Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jul 6;10(7):e0131742. doi: 10.1371/journal.pone.0131742

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

PMC Copyright notice

Fig 10 — Animal #3 (2.4 x 10⁷ PFU group). A) Hepatocellular degeneration and necrosis with prominent eosinophilic intracytoplasmic inclusions (arrows). HE. B) Immunohistochemistry demonstrates vaccinia viral antigen in the liver. Immunoperoxidase method with hematoxylin counterstain. C) Transmission electron micrograph of inclusion in hepatocyte. Note the varying stages of virion from immature (arrowheads) to mature (arrows). VP—viroplasm; M—mitochondira. D) Transmission electron micrograph of inclusion in hepatocyte containing endoplasmic reticulum (double arrowheads) and free ribosomes.