Table 2. Results from individual studies used for SNP selection in the present study.
Gene | SNP and position | Study | Phenotype |
---|---|---|---|
SCN5A | rs11720524 [C/G] intron 1 | Albert et al; 2010 [18] | Associated with cases of sudden and/or arrhytmic cardiac death in individuals of European ancestry |
RYR2 | rs790896 [A/G] 3′-UTR | Ran et al; 2010 [22] | Associated with sudden cardiac death in patients with chronic heart failure in Chinese Han population |
ADRB2 | rs1042714 [C/G] exon 1 | Kulminski et al; 2010 [32] | Associated with the incidence of myocardial infarction in Framingham Heart Study Offspring cohort |
TGFBR2 | rs9838682 [A/G] intron 3 | Tseng et al; 2009 [29] | Associate with sudden cardiac arrest in Caucasian patients with coronary artery disease |
NOS1AP | rs10494366 [G/T] intron 1 | Aarnoudse et al; 2007 [34] | Associated with the QT interval duration in Rotterdam Study cohort |
HR = hazard ratio; OR = odds ratio.