Table 3.
Variable | Control (n=33) | Group 1: patients given atorvastatin 20 mg/day (n=110)
|
Group 2: patients given atorvastatin 40 mg/day (n=100)
|
||
---|---|---|---|---|---|
Day 1 | Day 12 | Day 1 | Day 12 | ||
TC (mmol/L) | 4.5 (3.8; 4.6) | 5.50 (4.3; 7.4)a | 4.90 (4.3; 6.0)a,c | 5.8 (4.7; 7.4)a | 4.5 (3.9; 5.8)b,c |
LDL (mmol/L) | 2.26 (1.9; 2.3) | 2.92 (2.2; 3.3)a | 2.76 (1.7; 3.6) | 2.7 (2.0; 3.8)a | 2.5 (1.9; 3.2)b,c |
HDL (mmol/L) | 1.26 (1.1; 1.3) | 0.88 (0.8; 1.1)a | 0.95 (0.77; 1.13)a | 0.9 (0.6; 1.2)a | 1.0 (0.9; 1.2)a,c |
VLDL (mmol/L) | 0.56 (0.4; 0.9) | 1.10 (0.9; 1.4)a | 1.03 (0.71; 1.46)a | 11.2 (0.9; 1.3)a | 0.6 (0.5; 0.9)c |
apo-A1 (g/L) | 1.54 (1.3; 1.65) | 1.10 (0.9; 1.4)a | 1.23 (1.0; 1.6)a,c | 1.1 (0.9; 1.2)a | 1.3 (1.15; 1.54)a,c |
apo-B (g/L) | 1.19 (1.0; 1.5) | 1.75 (1.2; 1.9)a | 1.74 (1.07; 2.1)a | 1.7 (1.2; 1.9)a | 1.6 (1.1; 1.8)b |
TG (mmol/L) | 1.50 (1.4; 1.7) | 2.17 (1.5; 3.4)a | 2.10 (1.4; 2.8)a | 2.4 (1.9; 2.8)a | 2.0 (1.7; 2.4)c |
apo-B/apo-A1 | 0.81 (0.7; 1.0) | 1.48 (0.9; 1.8)a | 1.24 (0.3; 1.8)a | 1.3 (1.0; 1.9)a | 1.0 (0.7; 1.5)c |
FFA (mmol/L) | 0.35 (0.2; 0.4) | 1.92 (1.0; 2.0)a | 0.53 (0.7; 1.2)c | 1.8 (1.1; 2.0)a | 0.8 (0.5; 1.0)b,c |
Notes:
Significant difference from control (P<0.05).
Significant difference in indicator among groups on the 12th day.
Significant difference in indicator within the group on the first and 12th days.
Abbreviations: TC, total cholesterol; LDL, low-density lipoprotein cholesterol; HDL, high-density lipoprotein cholesterol; VLDL, very-low-density lipoprotein cholesterol; apo-A1, apolipoprotein A1; apo-B, apolipoprotein B; TG, triglyceride; FFA, free fatty acid.