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. 2015 Jun 26;9:1155–1157. doi: 10.2147/OPTH.S81089

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© 2015 Dua et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Difference between type 1 and type 2 big bubbles.

Notes: (A) The anterior surface of the Dua’s layer after creation of a type 1 big bubble. The broken strands or fibers of collagen give the surface a rough-looking appearance and is characteristic of cleavage having occurred between deep corneal stroma and the anterior surface of Dua’s layer. (B) The anterior surface of the Descemet’s membrane exposed after creation of a type 2 big bubble. The surface is very smooth and featureless with no visible fibers. This type of bubble is more susceptible to rupture or tear as it is not protected by Dua’s layer.