Table 3.

Univariate and multivariate analysis for overall survival

Variables	Univariate analyses HR for death (95% CI)	P-value	Multivariate analysis HR for death (95% CI)	P-value
Age	1.05 (0.67–1.66)	0.830	0.93 (0.58–1.48)	0.752
Sex	1.08 (0.69–1.71)	0.728	1.02 (0.64–1.63)	0.921
Smoking	1.55 (0.98–2.47)	0.062	1.56 (0.97–2.5)	0.065
Histology	0.96 (0.61–1.51)	0.849	0.74 (0.45–1.19)	0.214
Differentiation	0.97 (0.70–1.33)	0.844	0.94 (0.68–1.32)	0.736
Tumor size	1.05 (0.67–1.65)	0.834	0.93 (0.58–1.49)	0.769
Lymph node metastasis	2.47 (1.50–4.06)	<0.001	2.09 (1.24–3.51)	0.006
TNM stage	2.87 (1.58–5.24)	0.001	2.51 (1.34–4.7)	0.004
Fascin-1 expression	1.99 (1.22–3.23)	0.006	1.7 (1.02–2.83)	0.043

Abbreviations: CI, confidence interval; HR, hazard ratio.