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. 2015 Jul 6;10(7):e0131740. doi: 10.1371/journal.pone.0131740

Table 4. Association between serum 25-hydroxyvitamin D and C-reactive protein in subjects with data on osteoporosis available.

N Model 1 Model 2 Model 3
Beta (95% CI) Beta (95% CI) Beta (95% CI)
<50 nmol/l 1,579 Reference Reference Reference
50–75 nmol/l 749 -0.22 (-0.31, -0.12) -0.12 (-0.21, -0.03) -0.12 (-0.21, -0.03)
>75 nmol/l 418 -0.26 (-0.37, -0.14) -0.15 (-0.26, -0.04) -0.15 (-0.26, -0.04)
P for trend 6.15×10−7 0.003 0.003
Per SD 25OHD* 2,746 -0.12 (-0.17, -0.08) -0.07 (-0.12, -0.03) -0.07 (-0.11, -0.02)
P-value 5.48×10−7 0.004 0.004

Model 1: adjusted for age and sex

Model 2: adjusted for age, sex, body mass index, total cholesterol to high-density lipoprotein ratio, systolic blood pressure, prevalent diabetes mellitus, estimated glomerular filtration rate, smoking, alcohol intake, season and level of education

Model 3: additionally adjusted for osteoporosis

* 25OHD denotes 25-hydroxyvitamin D.