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CORM-3 treatment depletes iron levels in wild-type and heme-deficient E. coli cells over time. Intracellular iron levels in hemA (closed circles) and wild-type (open circles) cells were measured by ICP-AES over a time-course of 120 min after exposure of cultures to 100 μM CORM-3. Data are plotted as means±SEM from ≥3 biological replicates.
