Table 3.
Determinants of baseline FCP levels from multivariate analyses, stratified by baseline DA status
| Determinant | DA positive
|
DA negative
|
||
|---|---|---|---|---|
| Effect, % (95% CI)a | p value | Effect, % (95% CI)a | p value | |
| Age at diagnosis (<10 vs ≥10 years) | 44 (38, 49) | <0.0001 | 57 (47, 65) | <0.0001 |
| Sex (male vs female) | 11 (2, 19) | 0.0185 | 0.1 | |
| Race (NHW vs others) | 19 (9, 28) | 0.0004 | 30 (15, 42) | 0.0002 |
| HLA (susceptible vs not susceptible) | 0.7 | 0.5 | ||
| Baseline HbA1c (per 1% increase) | 19 (15, 22) | <0.0001 | 7 (1, 13) | 0.0170 |
| Baseline BMI z score (per 1 unit decrease) | 17 (13, 21) | <0.0001 | 37 (32, 42) | <0.0001 |
Percentage by which baseline FCP level is lower