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. 2015 May 4;3(3):e00136. doi: 10.1002/prp2.136

Table 3.

Effect of saroglitazar on glucose infusion rate, blood glucose, and serum insulin levels at the end of the clamp experiments in Zucker fa/fa rats.

Parameters Control Saroglitazar (1 mg/kg) Saroglitazar (10 mg/kg)
Glucose infusion rate (mg/kg per min) 11.6 ± 1.3 18.6 ± 1.6* 24.5 ± 2.6*
Glucose (mg/dL) 113.9 ± 4.5 111.3 ± 2.4 116.0 ± 1.9
Insulin (ng/mL) 17.6 ± 0.8 15.3 ± 0.8 15.0 ± 0.8

All values are measured at the end of clamp at 120 min after 15 days oral treatment and expressed as mean ± SEM. (n ≥ 6).

*

P < 0.05 as compared to control (ANOVA).