Table 4.
Effect of Saroglitazar on serum TG, adiponectin levels, and SBP in Zucker fa/fa rats.
| Group | Serum triglycerides (mg/dL) | Serum adiponectin (μg/mL) | SBP (mmHg) |
|---|---|---|---|
| Control | 640.5 ± 91.8 | 5.3 ± 0.5 | 134.0 ± 2.8 |
| Saroglitazar (4 mg/kg) | 122.0 ± 8.1* | 8.2 ± 0.5* | 112.5 ± 2.6* |
| Pioglitazone (10 mg/kg) | 332.8 ± 64.0* | 7.5 ± 1.1 | 113.4 ± 2.4* |
| Fenofibrate (100 mg/kg) | 295.5 ± 85.6* | 4.3 ± 0.4 | 124.0 ± 5.3 |
Serum triglyceride and adiponectin levels were measured on (14th day) and SBP was measured on day 15th by noninvasive blood pressure measurement method, all values expressed as mean ± SEM. (n = 7).
*
P < 0.05 as compared to control (ANOVA).