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In the dorsal horn of lumbar (L4-L6) spinal cord of vehicle-treated RR-EAE mice, pERK is colocalized predominantly with (A) CD3+ T cells. It is also colocalized with a subset of (B) neurons (NeuN) and to a lesser extent with (C) microglia/macrophages (CD11b) and (D) a subset of astrocytes (GFAP). Scale bars represent 20 μm.
