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. 2015 May 15;3(3):e00148. doi: 10.1002/prp2.148

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© 2015 The Authors. Pharmacology Research & Perspectives published by John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Expression profile of biomarkers in HK-2 cells after nephrotoxic compound treatment for 72 h. (A) KIM-1 protein concentration in culture medium; (B) KIM-1 protein concentration in cell lysates; (C) NGAL protein concentration in culture medium; (D) NGAL protein concentration in cell lysates; (E) M-CSF protein concentration in culture medium; and (F) M-CSF protein concentration in cell lysates. Data are presented as Mean ± Standard deviation. Significantly different *P < 0.05; **P < 0.01; ***P < 0.005, n ≥ 3 (three independent assays with two technical replicates in each assay).