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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Surgery. 2015 May 16;158(2):445–452. doi: 10.1016/j.surg.2015.03.034

Figure 3. Results of Calpain Inhibition on Anti-Apoptotic Protein Signaling in Ischemic Myocardial hypermetabolic Pig Tissue.

Figure 3

There was a significant increase in anti-apoptotic proteins including p-AKT (p=0.0001), p-eNOS (p= 0.003) and eNOS (p=0.006), BCL-2 (p= 0.025) and p-BCL2 (p= 0.004) with an insignificant increase seen in AKT (p=0.311). Results figured as ratios of active form of protein (phosphorylated) to inactive form of protein where appropriate. All numbers are load controlled to GAPDH and normalized to HCC. (*)= p<0.05 versus HCC by ANOVA (Kruskal-Wallace)